Reaction Details  Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM50152965
Substrate
n/a
Meas. Tech.
ChEMBL_302701 (CHEMBL876781)
Ki
90000±n/a nM
Citation
 Innocenti, A; Zimmerman, S; Ferry, JG; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions. Bioorg Med Chem Lett 14:4563-7 (2004) [PubMed]  Article
Target
Name:
Carbonic anhydrase
Synonyms:
CAH_METTT | CAM | Carbonic anhydrase | Gamma-carbonic anhydrase
Type:
Protein
Mol. Mass.:
26390.56
Organism:
Methanosarcina thermophila
Description:
P40881
Residue:
247
Sequence:
MMFNKQIFTILILSLSLALAGSGCISEGAEDNVAQEITVDEFSNIRENPVTPWNPEPSAPVIDPTAYIDPQASVIGEVTIGANVMVSPMASIRSDEGMPIFVGDRSNVQDGVVLHALETINEEGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGNNCVLEPRSAAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVHLAEGYKETS
  
Inhibitor
Name:
BDBM50152965
Synonyms:
(methylidyneammoniumyl)oxidanide | CHEMBL185198 | H-C#NO | HCNO | Knallsaeure | [C(H)NO] | [CH(NO)] | formonitrile oxideformonitrile-N-oxidehydrido(nitrosyl-kappaN)carbonhydrido(oxidonitrato-N)carbon | fulminic acid | hydrogen cyanide N-oxide | methylidyne(oxo)-lambda(5)-azane
Type:
Small organic molecule
Emp. Form.:
CHNO
Mol. Mass.:
43.0247
SMILES:
[O-]N=[CH+]
Structure:
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