Reaction Details  Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM82247
Substrate
n/a
Meas. Tech.
ChEMBL_303388 (CHEMBL839015)
Ki
8.1±n/a nM
Citation
 Di Stefano, A; Sozio, P; Cacciatore, I; Cocco, A; Giorgioni, G; Costa, B; Montali, M; Lucacchini, A; Martini, C; Spoto, G; Di Pietrantonio, F; Di Matteo, E; Pinnen, F Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists. J Med Chem 48:2646-54 (2005) [PubMed]  Article
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM82247
Synonyms:
8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390) | CAS_87134-87-0 | CHEMBL2158641 | CHEMBL62 | SCH 23388 | SCH 23390 | SCH 23390 (R-enantiomer) | SCH 23390,R(+)
Type:
Small organic molecule
Emp. Form.:
C17H18ClNO
Mol. Mass.:
287.784
SMILES:
CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: