Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50215245
Substrate
n/a
Meas. Tech.
ChEMBL_437161 (CHEMBL906558)
Ki
560±n/a nM
Citation
 Brizzi, A; Cascio, MG; Brizzi, V; Bisogno, T; Dinatolo, MT; Martinelli, A; Tuccinardi, T; Di Marzo, V Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. Bioorg Med Chem 15:5406-16 (2007) [PubMed]  Article
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50215245
Synonyms:
11-(3-hydroxy-5-pentyl-phenoxy)-undecanoic acid [2-(3,4-dihydroxy-phenyl)-ethyl]-amide | CHEMBL228349
Type:
Small organic molecule
Emp. Form.:
C30H45NO5
Mol. Mass.:
499.682
SMILES:
CCCCCc1cc(O)cc(OCCCCCCCCCCC(=O)NCCc2ccc(O)c(O)c2)c1
Structure:
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