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Target
P2Y purinoceptor 4
Ligand
BDBM50197694
Substrate
n/a
Meas. Tech.
ChEMBL_453276 (CHEMBL902431)
EC50
4233±n/a nM
Citation
 Davenport, RJ; Diaz, P; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP. Bioorg Med Chem Lett 17:558-61 (2007) [PubMed]  Article
Target
Name:
P2Y purinoceptor 4
Synonyms:
NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor
Type:
PROTEIN
Mol. Mass.:
40977.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_751027
Residue:
365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
  
Inhibitor
Name:
BDBM50197694
Synonyms:
({[({[(2R,3S,4R,5R)-5-(6-chloro-4-fluoro-1,3-benzothiazol-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | CHEMBL392989
Type:
Small organic molecule
Emp. Form.:
C12H14ClFNO13P3S
Mol. Mass.:
559.676
SMILES:
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)c1nc2c(F)cc(Cl)cc2s1 |w:13.14,9.10|
Structure:
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