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Target
Cannabinoid receptor 2
Ligand
BDBM50222840
Substrate
n/a
Meas. Tech.
ChEMBL_458048 (CHEMBL925386)
IC50
1000±n/a nM
Citation
 Ohta, H; Ishizaka, T; Tatsuzuki, M; Yoshinaga, M; Iida, I; Tomishima, Y; Toda, Y; Saito, S N-Alkylidenearylcarboxamides as new potent and selective CB(2) cannabinoid receptor agonists with good oral bioavailability. Bioorg Med Chem Lett 17:6299-304 (2007) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50222840
Synonyms:
3-(cyclopropylmethyl)-N,N,4-trimethyl-2-(3-(trifluoromethyl)benzamido)-2,3-dihydrothiazole-5-carboxamide | CHEMBL248202
Type:
Small organic molecule
Emp. Form.:
C19H20F3N3O2S
Mol. Mass.:
411.441
SMILES:
CN(C)C(=O)c1s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n(CC2CC2)c1C
Structure:
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