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Target
Cannabinoid receptor 2
Ligand
BDBM50377705
Substrate
n/a
Meas. Tech.
ChEMBL_479932 (CHEMBL929255)
EC50
9.3±n/a nM
Citation
 Worm, K; Zhou, QJ; Saeui, CT; Green, RC; Cassel, JA; Stabley, GJ; DeHaven, RN; Conway-James, N; LaBuda, CJ; Koblish, M; Little, PJ; Dolle, RE Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands. Bioorg Med Chem Lett 18:2830-5 (2008) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Human
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50377705
Synonyms:
CHEMBL442447
Type:
Small organic molecule
Emp. Form.:
C24H34N2O4S
Mol. Mass.:
446.603
SMILES:
CC(NC(=O)c1ccc(C)c(c1)S(=O)(=O)N1CCOCC1)C12CC3CC(CC(C3)C1)C2 |w:1.0,TLB:24:25:29:22.23.28,28:23:30:29.27.26,28:27:30:22.23.24,THB:24:23:29:30.25.26|
Structure:
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