Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50263032
Substrate
n/a
Meas. Tech.
ChEMBL_490516 (CHEMBL981122)
Ki
280±n/a nM
Citation
 Urbani, P; Cascio, MG; Ramunno, A; Bisogno, T; Saturnino, C; Di Marzo, V Novel sterically hindered cannabinoid CB1 receptor ligands. Bioorg Med Chem 16:7510-5 (2008) [PubMed]  Article
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50263032
Synonyms:
CHEMBL476317 | N-(3,3-Diphenyl)propyl-2-chloro-2,2-diphenylacetamide
Type:
Small organic molecule
Emp. Form.:
C29H26ClNO
Mol. Mass.:
439.976
SMILES:
ClC(C(=O)NCCC(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1
Structure:
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