Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50263115
Substrate
n/a
Meas. Tech.
ChEMBL_490516 (CHEMBL981122)
Ki
560±n/a nM
Citation
 Urbani, P; Cascio, MG; Ramunno, A; Bisogno, T; Saturnino, C; Di Marzo, V Novel sterically hindered cannabinoid CB1 receptor ligands. Bioorg Med Chem 16:7510-5 (2008) [PubMed]  Article
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50263115
Synonyms:
2-(4-Nitrophenyl)-2-phenyl-N-(3,3-diphenylpropyl)-acetamide | CHEMBL479094
Type:
Small organic molecule
Emp. Form.:
C29H26N2O3
Mol. Mass.:
450.5283
SMILES:
[O-][N+](=O)c1ccc(cc1)C(C(=O)NCCC(c1ccccc1)c1ccccc1)c1ccccc1
Structure:
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