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Target
Mu-type opioid receptor
Ligand
BDBM50381665
Substrate
n/a
Meas. Tech.
ChEMBL_816181 (CHEMBL2026565)
Ki
>1700±n/a nM
Citation
 Lovell, KM; Vasiljevik, T; Araya, JJ; Lozama, A; Prevatt-Smith, KM; Day, VW; Dersch, CM; Rothman, RB; Butelman, ER; Kreek, MJ; Prisinzano, TE Semisynthetic neoclerodanes as kappa opioid receptor probes. Bioorg Med Chem 20:3100-10 (2012) [PubMed]  Article
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50381665
Synonyms:
CHEMBL2022306
Type:
Small organic molecule
Emp. Form.:
C23H30O8
Mol. Mass.:
434.4795
SMILES:
COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)C(=O)C=CC |r,w:29.32|
Structure:
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