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Target
Cathepsin G
Ligand
BDBM50384104
Substrate
n/a
Meas. Tech.
ChEMBL_819861 (CHEMBL2034575)
IC50
100000±n/a nM
Citation
 Santana, AB; Lucas, SD; Gonçalves, LM; Correia, HF; Cardote, TA; Guedes, RC; Iley, J; Moreira, R N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases. Bioorg Med Chem Lett 22:3993-7 (2012) [PubMed]  Article
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50384104
Synonyms:
CHEMBL2029559
Type:
Small organic molecule
Emp. Form.:
C17H13NO5
Mol. Mass.:
311.2888
SMILES:
COc1ccc(cc1)C(=O)n1c(O)c(oc1=O)-c1ccccc1
Structure:
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