Reaction Details  Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50386103
Substrate
n/a
Meas. Tech.
ChEMBL_824504 (CHEMBL2045249)
Ki
398.11±n/a nM
Citation
 Areias, F; Costa, M; Castro, M; Brea, J; Gregori-Puigjané, E; Proença, MF; Mestres, J; Loza, MI New chromene scaffolds for adenosine A(2A) receptors: synthesis, pharmacology and structure-activity relationships. Eur J Med Chem 54:303-10 (2012) [PubMed]  Article
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50386103
Synonyms:
CHEMBL1990267
Type:
Small organic molecule
Emp. Form.:
C11H10N2O3
Mol. Mass.:
218.2087
SMILES:
COc1cccc2cc(C(N)=O)c(=N)oc12
Structure:
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