Reaction Details  Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50386103
Substrate
n/a
Meas. Tech.
ChEMBL_824508 (CHEMBL2045253)
Ki
316.23±n/a nM
Citation
 Areias, F; Costa, M; Castro, M; Brea, J; Gregori-Puigjané, E; Proença, MF; Mestres, J; Loza, MI New chromene scaffolds for adenosine A(2A) receptors: synthesis, pharmacology and structure-activity relationships. Eur J Med Chem 54:303-10 (2012) [PubMed]  Article
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50386103
Synonyms:
CHEMBL1990267
Type:
Small organic molecule
Emp. Form.:
C11H10N2O3
Mol. Mass.:
218.2087
SMILES:
COc1cccc2cc(C(N)=O)c(=N)oc12
Structure:
Search PDB for entries with ligand similarity: