Reaction Details  Report a problem with these data
Target
Protein tyrosine phosphatase type IVA 1
Ligand
BDBM50391713
Substrate
n/a
Meas. Tech.
ChEMBL_848111 (CHEMBL2148512)
IC50
21000±n/a nM
Citation
 Park, H; Chien, PN; Ryu, SE Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening. Bioorg Med Chem Lett 22:6333-7 (2012) [PubMed]  Article
Target
Name:
Protein tyrosine phosphatase type IVA 1
Synonyms:
PRL1 | PTP4A1 | PTPCAAX1 | TP4A1_HUMAN
Type:
PROTEIN
Mol. Mass.:
19823.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461024
Residue:
173
Sequence:
MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
  
Inhibitor
Name:
BDBM50391713
Synonyms:
CHEMBL2146956
Type:
Small organic molecule
Emp. Form.:
C16H9N7S
Mol. Mass.:
331.355
SMILES:
c1ccc2nc(ccc2c1)-c1nnc2sc(nn12)-c1cnccn1
Structure:
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