Reaction Details  Report a problem with these data
Target
Protein tyrosine phosphatase type IVA 1
Ligand
BDBM50391712
Substrate
n/a
Meas. Tech.
ChEMBL_848111 (CHEMBL2148512)
IC50
>100000±n/a nM
Citation
 Park, H; Chien, PN; Ryu, SE Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening. Bioorg Med Chem Lett 22:6333-7 (2012) [PubMed]  Article
Target
Name:
Protein tyrosine phosphatase type IVA 1
Synonyms:
PRL1 | PTP4A1 | PTPCAAX1 | TP4A1_HUMAN
Type:
PROTEIN
Mol. Mass.:
19823.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461024
Residue:
173
Sequence:
MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
  
Inhibitor
Name:
BDBM50391712
Synonyms:
CHEMBL2146959
Type:
Small organic molecule
Emp. Form.:
C19H13N5O5S
Mol. Mass.:
423.402
SMILES:
[O-][N+](=O)c1ccccc1NC(=O)CSc1nnc(-c2ccco2)c(n1)-c1ccco1
Structure:
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