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Target
Protein tyrosine phosphatase type IVA 3
Ligand
BDBM50237957
Substrate
n/a
Meas. Tech.
ChEMBL_848112 (CHEMBL2148513)
IC50
>100000±n/a nM
Citation
 Park, H; Chien, PN; Ryu, SE Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening. Bioorg Med Chem Lett 22:6333-7 (2012) [PubMed]  Article
Target
Name:
Protein tyrosine phosphatase type IVA 3
Synonyms:
PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN
Type:
PROTEIN
Mol. Mass.:
19546.22
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461022
Residue:
173
Sequence:
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
  
Inhibitor
Name:
BDBM50237957
Synonyms:
4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-pyrrol-1-yl)benzoic acid | CHEMBL399586
Type:
Small organic molecule
Emp. Form.:
C15H11N3O4
Mol. Mass.:
297.2655
SMILES:
OC(=O)c1ccc(cc1)-n1cccc1\C=C1\NC(=O)NC1=O
Structure:
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