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Target
Prostaglandin E2 receptor EP4 subtype
Ligand
BDBM50394644
Substrate
n/a
Meas. Tech.
ChEMBL_857866 (CHEMBL2169499)
Ki
902±n/a nM
Citation
 Tomasch, M; Schwed, JS; Kuczka, K; Meyer Dos Santos, S; Harder, S; Nüsing, RM; Paulke, A; Stark, H Fluorescent Human EP3 Receptor Antagonists. ACS Med Chem Lett 3:774-779 (2012) [PubMed]  Article
Target
Name:
Prostaglandin E2 receptor EP4 subtype
Synonyms:
PE2R4_HUMAN | PGE receptor EP4 subtype | PGE2 receptor EP4 subtype | PTGER2 | PTGER4 | Prostaglandin E2 receptor | Prostanoid EP4 receptor
Type:
Enzyme
Mol. Mass.:
53134.53
Organism:
Homo sapiens (Human)
Description:
P35408
Residue:
488
Sequence:
MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
  
Inhibitor
Name:
BDBM50394644
Synonyms:
CHEMBL2164612
Type:
Small organic molecule
Emp. Form.:
C40H43N2O4
Mol. Mass.:
615.7799
SMILES:
COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCC[n+]1c(C)cc(\C=C\C=C\c2ccc(cc2)N(C)C)cc1C
Structure:
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