Reaction Details  Report a problem with these data
Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50394644
Substrate
n/a
Meas. Tech.
ChEMBL_857864 (CHEMBL2169497)
Ki
68625±n/a nM
Citation
 Tomasch, M; Schwed, JS; Kuczka, K; Meyer Dos Santos, S; Harder, S; Nüsing, RM; Paulke, A; Stark, H Fluorescent Human EP3 Receptor Antagonists. ACS Med Chem Lett 3:774-779 (2012) [PubMed]  Article
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM50394644
Synonyms:
CHEMBL2164612
Type:
Small organic molecule
Emp. Form.:
C40H43N2O4
Mol. Mass.:
615.7799
SMILES:
COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCC[n+]1c(C)cc(\C=C\C=C\c2ccc(cc2)N(C)C)cc1C
Structure:
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