Reaction Details  Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50398070
Substrate
n/a
Meas. Tech.
ChEMBL_873672 (CHEMBL2188788)
EC50
960±n/a nM
Citation
 Yelovitch, S; Barr, HM; Camden, J; Weisman, GA; Shai, E; Varon, D; Fischer, B Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist. J Med Chem 55:7623-35 (2012) [PubMed]  Article
Target
Name:
P2Y purinoceptor 1
Synonyms:
P2RY1 | P2RY1_MELGA
Type:
n/a
Mol. Mass.:
41199.64
Organism:
Meleagris gallopavo
Description:
n/a
Residue:
362
Sequence:
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
  
Inhibitor
Name:
BDBM50398070
Synonyms:
CHEMBL2181938
Type:
Small organic molecule
Emp. Form.:
C10H15BN5O9P2
Mol. Mass.:
422.014
SMILES:
[BH3-][P@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OP([O-])([O-])=O |r|
Structure:
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