Reaction Details  Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50403125
Substrate
n/a
Meas. Tech.
ChEBML_90019
IC50
100±n/a nM
Citation
 Klar, U; Pletsch, A New TXA2/PGH2 receptor antagonists based on the carbacyclin skeleton Bioorg Med Chem Lett 3:199-204 (1993)    Article
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50403125
Synonyms:
CHEMBL62937
Type:
Small organic molecule
Emp. Form.:
C21H27N3O4
Mol. Mass.:
385.4568
SMILES:
O[C@@H]1C[C@@H]2C\C(C[C@@H]2[C@H]1C=NNC(=O)Nc1ccccc1)=C\CCCC(O)=O |w:10.12|
Structure:
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