Reaction Details  Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50415878
Substrate
n/a
Meas. Tech.
ChEMBL_629908 (CHEMBL1108372)
Ki
1995.26±n/a nM
Citation
 Areias, FM; Brea, J; Gregori-Puigjané, E; Zaki, ME; Carvalho, MA; Domínguez, E; Gutiérrez-de-Terán, H; Proença, MF; Loza, MI; Mestres, J In silico directed chemical probing of the adenosine receptor family. Bioorg Med Chem 18:3043-52 (2010) [PubMed]  Article
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50415878
Synonyms:
CHEMBL1095872
Type:
Small organic molecule
Emp. Form.:
C18H15N5O3
Mol. Mass.:
349.3434
SMILES:
NC(=O)c1nc(-c2ccccc2O)n2CN(C(=N)c12)c1ccc(O)cc1
Structure:
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