Reaction Details  Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50419156
Substrate
n/a
Meas. Tech.
ChEMBL_770381 (CHEMBL1833690)
EC50
295.12±n/a nM
Citation
 Christiansen, E; Urban, C; Grundmann, M; Due-Hansen, ME; Hagesaether, E; Schmidt, J; Pardo, L; Ullrich, S; Kostenis, E; Kassack, M; Ulven, T Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties. J Med Chem 54:6691-703 (2011) [PubMed]  Article
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50419156
Synonyms:
CHEMBL1829159
Type:
Small organic molecule
Emp. Form.:
C16H12ClNO2
Mol. Mass.:
285.725
SMILES:
OC(=O)CCc1ccc(cc1)C#Cc1ccnc(Cl)c1
Structure:
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