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Target
Delta-type opioid receptor
Ligand
BDBM50422805
Substrate
n/a
Meas. Tech.
ChEMBL_334062 (CHEMBL861271)
IC50
25.1±n/a nM
Citation
 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Highly potent and selective zwitterionic agonists of the delta-opioid receptor. Part 1. Bioorg Med Chem Lett 16:905-10 (2006) [PubMed]  Article
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50422805
Synonyms:
CHEMBL370558
Type:
Small organic molecule
Emp. Form.:
C31H36FN3O2
Mol. Mass.:
501.6348
SMILES:
C[C@@H]1CN([C@H](c2ccc3CN(CCC(O)=O)Cc3c2)c2cccc(F)c2)[C@@H](C)CN1Cc1ccccc1
Structure:
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