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Target
Melatonin receptor type 1B
Ligand
BDBM50425194
Substrate
n/a
Meas. Tech.
ChEMBL_937789 (CHEMBL2318043)
Ki
6.8±n/a nM
Citation
 Morellato, L; Lefas-Le Gall, M; Langlois, M; Caignard, DH; Renard, P; Delagrange, P; Mathé-Allainmat, M Synthesis of new N-(arylcyclopropyl)acetamides and N-(arylvinyl)acetamides as conformationally-restricted ligands for melatonin receptors. Bioorg Med Chem Lett 23:430-4 (2012) [PubMed]  Article
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50425194
Synonyms:
CHEMBL2314250
Type:
Small organic molecule
Emp. Form.:
C15H15NO
Mol. Mass.:
225.2857
SMILES:
CC(=O)N[C@@H]1C[C@H]1c1cccc2ccccc12 |r|
Structure:
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