Reaction Details  Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50436903
Substrate
n/a
Meas. Tech.
ChEMBL_972128 (CHEMBL2406600)
Ki
12±n/a nM
Citation
 Hossain, N; Ivanova, S; Timén, ÅS; Bergare, J; Mussie, T; Bergström, L Design, synthesis and structure-activity relationships of zwitterionic spirocyclic compounds as potent CCR1 antagonists. Bioorg Med Chem Lett 23:4026-30 (2013) [PubMed]  Article
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50436903
Synonyms:
CHEMBL2401860
Type:
Small organic molecule
Emp. Form.:
C26H21F6N3O2S
Mol. Mass.:
553.519
SMILES:
CC(C)(C)c1ccccc1Oc1ncccc1Nc1nc(c(s1)-c1ccc(OC(F)(F)F)cc1)C(F)(F)F
Structure:
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