Reaction Details  Report a problem with these data
Target
Superoxide dismutase [Cu-Zn]
Ligand
BDBM50039027
Substrate
n/a
Meas. Tech.
ChEMBL_1444880 (CHEMBL3380222)
IC50
56600±n/a nM
Citation
 Olmo, F; Guardia, JJ; Marin, C; Messouri, I; Rosales, MJ; Urbanová, K; Chayboun, I; Chahboun, R; Alvarez-Manzaneda, EJ; Sánchez-Moreno, M Prospects of an alternative treatment against Trypanosoma cruzi based on abietic acid derivatives show promising results in Balb/c mouse model. Eur J Med Chem 89:683-90 (2014) [PubMed]  Article
Target
Name:
Superoxide dismutase [Cu-Zn]
Synonyms:
SOD1 | SODC_HUMAN | Superoxide dismutase
Type:
PROTEIN
Mol. Mass.:
15933.55
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1444880
Residue:
154
Sequence:
MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
  
Inhibitor
Name:
BDBM50039027
Synonyms:
CHEMBL3355357
Type:
Small organic molecule
Emp. Form.:
C20H28O4
Mol. Mass.:
332.4339
SMILES:
[H][C@@]12[C@@H](O)C(=O)c3cc(C(C)C)c(O)cc3[C@@]1(C)CCC[C@@]2(C)CO |r|
Structure:
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