Target
Cathepsin H
Ligand
BDBM50045438
Substrate
n/a
Meas. Tech.
ChEMBL_1459868 (CHEMBL3367291)
Ki
24320±n/a nM
Citation
 Raghav, NSingh, M SAR studies of differently functionalized chalcones based hydrazones and their cyclized derivatives as inhibitors of mammalian cathepsin B and cathepsin H. Bioorg Med Chem 22:4233-45 (2014) [PubMed]  Article
Target
Name:
Cathepsin H
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
37394.24
Organism:
Capra hircus (Goat)
Description:
A0A060INS8
Residue:
335
Sequence:
MWAVLPLLCAGAWLLGAPACGAAELAVNSLEKFHFQSWMVQHQKKYSSEEYHHRLQVFASNLREINAHNARNHTFKMGLNQFSDMSFAELKRKYLWSEPQNCSATKSNYLRGTGPYPPSMDWREKGNFVTPVKNQGSCGSCWTFSTTGALESAVAIATGKLPFLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYRGQDGDCKYQPSKAIAFVKDVANITLNDEEAMVEAVALYNPVSFAFEVTADFMMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEEKGIPYWIVKNSWGPHWGMKGYFLIERGKNMCGLAACASFPIPLV
  
Inhibitor
Name:
BDBM50045438
Synonyms:
CHEMBL3309798
Type:
Small organic molecule
Emp. Form.:
C17H15N3O3
Mol. Mass.:
309.3193
SMILES:
CC(=O)N1N=C(CC1c1ccc(cc1)[N+]([O-])=O)c1ccccc1 |c:4|
Structure:
Search PDB for entries with ligand similarity: