Reaction Details  Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM50064896
Substrate
n/a
Meas. Tech.
ChEMBL_1501217 (CHEMBL3587785)
Ki
8400±n/a nM
Citation
 Tarawneh, A; León, F; Pettaway, S; Elokely, KM; Klein, ML; Lambert, J; Mansoor, A; Cutler, SJ Flavonoids from Perovskia atriplicifolia and Their in Vitro Displacement of the Respective Radioligands for Human Opioid and Cannabinoid Receptors. J Nat Prod 78:1461-5 (2015) [PubMed]  Article
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50064896
Synonyms:
4,5-Dihydroxy-6-methoxy-2-(4-methoxy-phenyl)-chromen-7-one | 5,7-Dihydroxy-6-methoxy-2-(4-methoxy-phenyl)-chromen-4-one | 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one | CHEMBL78010 | NSC-106403 | Pectolinarigenin | cid_5320438
Type:
Small organic molecule
Emp. Form.:
C17H14O6
Mol. Mass.:
314.2895
SMILES:
COc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(O)cc2o1
Structure:
Search PDB for entries with ligand similarity: