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Target
Carbonic anhydrase 2
Ligand
BDBM50079047
Substrate
n/a
Meas. Tech.
ChEMBL_1552239 (CHEMBL3761241)
Ki
295±n/a nM
Citation
 Del Prete, S; Vullo, D; De Luca, V; Carginale, V; Ferraroni, M; Osman, SM; AlOthman, Z; Supuran, CT; Capasso, C Sulfonamide inhibition studies of the฿-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. Bioorg Med Chem 24:1115-20 (2016) [PubMed]  Article
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50079047
Synonyms:
3-Amino-benzenesulfonamide | 3-aminobenzenesulfonamide | CHEMBL6852
Type:
Small organic molecule
Emp. Form.:
C6H8N2O2S
Mol. Mass.:
172.205
SMILES:
Nc1cccc(c1)S(N)(=O)=O
Structure:
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