Reaction Details  Report a problem with these data
Target
Spermidine synthase
Ligand
BDBM50151659
Substrate
n/a
Meas. Tech.
ChEMBL_1561266 (CHEMBL3778086)
IC50
190000±n/a nM
Citation
 Simon, RP; Robaa, D; Alhalabi, Z; Sippl, W; Jung, M KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases. J Med Chem 59:1249-70 (2016) [PubMed]  Article
Target
Name:
Spermidine synthase
Synonyms:
Spermidine synthase
Type:
PROTEIN
Mol. Mass.:
10367.33
Organism:
Sus scrofa
Description:
ChEMBL_116912
Residue:
89
Sequence:
LDLIKEMRQFCKSLFPVVDYAYCTIPTYPSGQIGFMLCSKNPSTNFREPVQLLTQKQVEQRQLRYYNSDVHRAAFVLPEFARKALNDAD
  
Inhibitor
Name:
BDBM50151659
Synonyms:
CHEMBL3775244
Type:
Small organic molecule
Emp. Form.:
C32H24N4O4S2
Mol. Mass.:
592.687
SMILES:
COc1ccc(cc1OC)C1CC(=NN1c1nc(cs1)-c1ccc(cc1)N1C(=O)c2ccccc2C1=O)c1cccs1 |c:13|
Structure:
Search PDB for entries with ligand similarity: