Reaction Details  Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50167257
Substrate
n/a
Meas. Tech.
ChEMBL_1573754 (CHEMBL3802938)
Ki
>50000±n/a nM
Citation
 Hayashi, R; Ito, H; Ishigaki, T; Morita, Y; Miyamoto, M; Isogaya, M Piperidine derivatives as nonprostanoid IP receptor agonists 2. Bioorg Med Chem Lett 26:2886-2889 (2016) [PubMed]  Article
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50167257
Synonyms:
CHEMBL3798917
Type:
Small organic molecule
Emp. Form.:
C24H31ClN2O7
Mol. Mass.:
494.965
SMILES:
O.Cl.Cc1ccc(cc1)N(CCN1CCC(CC1)OCC(O)=O)C(=O)c1ccc2OCOc2c1
Structure:
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