Reaction Details  Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50420167
Substrate
n/a
Meas. Tech.
ChEMBL_1589785 (CHEMBL3830337)
EC50
471±n/a nM
Citation
 Liu, Y; Zhang, Q; Chen, LH; Yang, H; Lu, W; Xie, X; Nan, FJ Design and Synthesis of 2-Alkylpyrimidine-4,6-diol and 6-Alkylpyridine-2,4-diol as Potent GPR84 Agonists. ACS Med Chem Lett 7:579-83 (2016) [PubMed]  Article
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50420167
Synonyms:
CHEMBL2058533
Type:
Small organic molecule
Emp. Form.:
C23H21FO3
Mol. Mass.:
364.4094
SMILES:
Cc1ccc(cc1)-c1ccc(F)cc1COc1ccc(CCC(O)=O)cc1
Structure:
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