Reaction Details  Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50200983
Substrate
n/a
Meas. Tech.
ChEMBL_1622887 (CHEMBL3865239)
Ki
9.6±n/a nM
Citation
 Rosse, G Quinazoline Carboxamides as Selective Antagonists of Adenosine 2A Receptor. ACS Med Chem Lett 7:1014-1015 (2016) [PubMed]  Article
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50200983
Synonyms:
CHEMBL3981924 | US10138212, Example 57
Type:
Small organic molecule
Emp. Form.:
C16H14FN5O2
Mol. Mass.:
327.3131
SMILES:
Nc1nc(C(=O)NCc2cccc(CO)n2)c2cccc(F)c2n1
Structure:
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