Reaction Details  Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM50212636
Substrate
n/a
Meas. Tech.
ChEMBL_40896 (CHEMBL653649)
IC50
7.55±n/a nM
Citation
  TBA Bioorg Med Chem Lett 3:2247-2252 (1993)  
Target
Name:
Beta-lactamase
Synonyms:
BLAC_PROMI | Beta-lactamase | Carbenicillinase | blaP
Type:
PROTEIN
Mol. Mass.:
32766.94
Organism:
Proteus mirabilis
Description:
ChEMBL_101534
Residue:
298
Sequence:
MNVRQHKASFFSVVITFLCLTLSLNANATDSVLEAVTNAETELGARIGLAAHDLETGKRWEHKSNERFPLSSTFKTLACANVLQRVDLGKERIDRVVRFSESNLVTYSPVTEKHVGKKGMSLAELCQATLSTSDNSAANFILQAIGGPKALTKFLRSIGDDTTRLDRWEPELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQQLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITETDASFEERNAVIAKIGEQIAKTVLMENSRN
  
Inhibitor
Name:
BDBM50212636
Synonyms:
CHEMBL310221
Type:
Small organic molecule
Emp. Form.:
C11H13BrN2O3S3
Mol. Mass.:
397.332
SMILES:
[H][C@]12S[C@@](C)(CSC3=NCCS3)[C@@H](N1C(=O)[C@H]2Br)C(O)=O |t:7|
Structure:
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