Reaction Details  Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50230955
Substrate
n/a
Meas. Tech.
ChEMBL_1645057 (CHEMBL3993986)
Ki
0.300000±n/a nM
Citation
 Landagaray, E; Ettaoussi, M; Rami, M; Boutin, JA; Caignard, DH; Delagrange, P; Melnyk, P; Berthelot, P; Yous, S New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation. Eur J Med Chem 127:621-631 (2017) [PubMed]  Article
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50230955
Synonyms:
CHEMBL4102177
Type:
Small organic molecule
Emp. Form.:
C14H16N2O2
Mol. Mass.:
244.289
SMILES:
COc1ccc2cccc(CCNC(C)=O)c2n1
Structure:
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