Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 4
Ligand
BDBM84648
Substrate
n/a
Ki
25.11±n/a nM
Comments
PDSP_400
Citation
 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor. FEBS Lett 398:19-25 (1996) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT-4 | 5-HT4 | 5-HT4L | 5-hydroxytryptamine receptor 4 | 5HT4R_MOUSE | Htr4 | Serotonin 4 (5-HT4) receptor | Serotonin receptor 4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43970.99
Organism:
MOUSE
Description:
5-HT4 HTR4 MOUSE::P97288
Residue:
388
Sequence:
MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT
  
Inhibitor
Name:
BDBM84648
Synonyms:
BIMU 8
Type:
Small organic molecule
Emp. Form.:
C19H26N4O2
Mol. Mass.:
342.4353
SMILES:
CC(C)n1c2ccccc2n(C(=O)NC2C[C@@H]3CC[C@H](C2)N3C)c1=O
Structure:
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