Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 4
Ligand
BDBM85020
Substrate
n/a
Ki
0.19±n/a nM
Comments
PDSP_881
Citation
 Van den Wyngaert, I; Gommeren, W; Verhasselt, P; Jurzak, M; Leysen, J; Luyten, W; Bender, E Cloning and expression of a human serotonin 5-HT4 receptor cDNA. J Neurochem 69:1810-9 (1997) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43735.29
Organism:
GUINEA PIG
Description:
5-HT4 HTR4 GUINEA PIG::O70528
Residue:
388
Sequence:
MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRPQPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDTVECGGQWESQCHPAASSPLVAAQPIDT
  
Inhibitor
Name:
BDBM85020
Synonyms:
5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-[2-[(methylsulfonyl)amino]ethyl]piperidin-4-yl]methyl ester | GR 125487 | GR-125487
Type:
Small organic molecule
Emp. Form.:
C19H26FN3O5S
Mol. Mass.:
427.49
SMILES:
n/a
Structure:
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