Reaction Details  Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM85724
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_7430
Citation
 Reubi, JC; Schaer, JC; Wenger, S; Hoeger, C; Erchegyi, J; Waser, B; Rivier, J SST3-selective potent peptidic somatostatin receptor antagonists. Proc Natl Acad Sci U S A 97:13973-8 (2000) [PubMed]  Article
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM85724
Synonyms:
des-AA 1,2,4,5,12,13[DAgl8(Me,2-naphthoyl)]-SS
Type:
Small organic molecule
Emp. Form.:
C57H68N10O11S2
Mol. Mass.:
1133.34
SMILES:
C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)N(C)C(=O)c1ccc2ccccc2c1
Structure:
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