Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM85857
Substrate
n/a
Ki
1290±n/a nM
Comments
PDSP_2211
Citation
 Di Marzo, V; Griffin, G; De Petrocellis, L; Brandi, I; Bisogno, T; Williams, W; Grier, MC; Kulasegram, S; Mahadevan, A; Razdan, RK; Martin, BR A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. J Pharmacol Exp Ther 300:984-91 (2002) [PubMed]  Article
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM85857
Synonyms:
O-2093
Type:
Small organic molecule
Emp. Form.:
C34H43Cl2NO3
Mol. Mass.:
584.616
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)N(Cc1ccc(O)c(Cl)c1)Cc1ccc(O)c(Cl)c1
Structure:
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