Reaction Details  Report a problem with these data
Target
Promotilin
Ligand
BDBM86001
Substrate
n/a
Ki
6918.31±n/a nM
Comments
PDSP_6185
Citation
 Thielemans, L; Depoortere, I; Vanden Broeck, J; Peeters, TL The motilin pharmacophore in CHO cells expressing the human motilin receptor. Biochem Biophys Res Commun 293:1223-7 (2002) [PubMed]  Article
Target
Name:
Promotilin
Synonyms:
MLN | MOTI_HUMAN | Motilin | Promotilin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12919.83
Organism:
Homo sapiens (Human)
Description:
Motilin 0 HUMAN::P12872
Residue:
115
Sequence:
MVSRKAVAALLVVHVAAMLASQTEAFVPIFTYGELQRMQEKERNKGQKKSLSVWQRSGEEGPVDPAEPIREEENEMIKLTAPLEIGMRMNSRQLEKYPATLEGLLSEMLPQHAAK
  
Inhibitor
Name:
BDBM86001
Synonyms:
[leu13]pMOT(1-7)
Type:
Small organic molecule
Emp. Form.:
C47H64N8O9
Mol. Mass.:
885.0593
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r|
Structure:
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