Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM113767
Substrate
n/a
Meas. Tech.
CB1 & 2 Binding Assays
pH
7.4±n/a
Temperature
303.15±n/a K
Ki
>1.0e+4±n/a nM
Comments
extracted
Citation
 Chicca, A; Caprioglio, D; Minassi, A; Petrucci, V; Appendino, G; Taglialatela-Scafati, O; Gertsch, J Functionalization of ß-Caryophyllene Generates Novel Polypharmacology in the Endocannabinoid System. ACS Chem Biol 9:1499-507 (2014) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM113767
Synonyms:
(E)-6-((1R,2R)-3,3-Dimethyl-2-(3-methylbut-3-enyl)cyclobutyl)-N-(4-hydroxy-3-methoxybenzyl)hepta-2,6-dienamide (11e)
Type:
Small organic molecule
Emp. Form.:
C26H37NO3
Mol. Mass.:
411.5769
SMILES:
COc1cc(CNC(=O)\C=C\CCC(=C)[C@@H]2CC(C)(C)[C@@H]2CCC(C)=C)ccc1O
Structure:
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