Reaction Details  Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM128306
Substrate
n/a
Meas. Tech.
Competition Radioligand Binding Assay
Temperature
298.15±n/a K
Ki
8±n/a nM
Comments
extracted
Citation
 Camacho Gomez, JA; Castro-Palomino Laria, JC 4-aminopyrimidine derivatives and their as as adenosine A2a receptor antagonists US Patent  US8796284 Publication Date 8/5/2014
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM128306
Synonyms:
US8796284, 36
Type:
Small organic molecule
Emp. Form.:
C9H10BrN5S
Mol. Mass.:
300.178
SMILES:
CCSc1nc(nc(N)c1Br)-n1cccn1
Structure:
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