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Target
Beta-lactamase
Ligand
BDBM159601
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7±n/a
IC50
>3.0e+4±n/a nM
Comments
extracted
Citation
 Abe, T; Okue, M; Sakamaki, Y Process for preparing a compound useful for producing an optically active diazabicyclooctane compound US Patent  US9035062 Publication Date 5/19/2015
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM159601
Synonyms:
US8772490, Example 24 | US9035062, 24
Type:
Small organic molecule
Emp. Form.:
C7H10N3NaO6S
Mol. Mass.:
287.226
SMILES:
NC(=O)[C@H]1CC[C@H]2CN1C(=O)N2OS(=O)(=O)O[Na] |r|
Structure:
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