Reaction Details  Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM458394
Substrate
n/a
Meas. Tech.
Competition Radioligand Binding Assay
Ki
>1000±n/a nM
Citation
 Castro Palomino Laria, J; Camacho Gómez, J; El Maatougui, A Adenosine A3 receptor modulators US Patent  US10744125 Publication Date 8/18/2020
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM458394
Synonyms:
US10744125, Example 4
Type:
Small organic molecule
Emp. Form.:
C23H21N5O4S
Mol. Mass.:
463.509
SMILES:
COc1ccc(cc1)-c1nc(NC(=O)c2ccc(nc2)N2CCC(CC2)C(O)=O)sc1C#N
Structure:
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