Reaction Details  Report a problem with these data
Target
Amyloid-beta precursor protein [1-42]
Ligand
BDBM481156
Substrate
n/a
Meas. Tech.
In Vitro Direct Determination By Fluorescence
Kd
3.60±2 nM
Citation
 Routier, S; Suzenet, F; Chalon, S; Buron, F; Vercouillie, J; Melki, R; Boiaryna, L; Guilloteau, D; Pieri, L Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases US Patent  US10906900 Publication Date 2/2/2021
Target
Name:
Amyloid-beta precursor protein [1-42]
Synonyms:
A4 | A4_HUMAN | AD1 | APP | Amyloid-beta precursor protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3256.81
Organism:
Homo sapiens (Human)
Description:
aa 1-42
Residue:
32
Sequence:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEP
  
Inhibitor
Name:
BDBM481156
Synonyms:
US10906900, Reference 22d
Type:
Small organic molecule
Emp. Form.:
C17H15N3
Mol. Mass.:
261.3211
SMILES:
CN(C)c1ccc(cc1)C#Cc1cc2cnccc2[nH]1
Structure:
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