Target

Ligand

Substrate

Meas. Tech.

Kinase Inhibition Assay

pH

7.5±n/a

Temperature

310.15±n/a K

Citation

 Martinez, A; Alonso, M; Castro, A; Dorronsoro, I; Gelpi, JL; Luque, FJ; Perez, C; Moreno, FJ SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors. J Med Chem 48:7103-12 (2005) [PubMed]  Article

More Info.:

Get all data from this article,  Inhibition_Run data,   Solution Info,  Assay Method

Name:

Glycogen synthase kinase-3 beta [7-25]

Synonyms:

G1T8E2_RABIT | GSK-3, beta | GSK3B | Glycogen Synthase Kinase-3, beta

Type:

Enzyme fragment

Mol. Mass.:

1972.14

Organism:

Oryctolagus cuniculus (rabbit)

Description:

Glycogen Synthase Kinase-3 is the beta isoform of the rabbit enzyme produced in E.coli.. Only partial sequence is available.

Residue:

19

Sequence:

TTSFAESCKPVQQPSAFGS

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM7805

Synonyms:

Maleimide-Related Compound 4 | N-(Ethoxycarbonylmethyl)-maleimide | ethyl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate

Type:

Small organic molecule

Emp. Form.:

C8H9NO4

Mol. Mass.:

183.1614

SMILES:

CCOC(=O)CN1C(=O)C=CC1=O |c:9|

Structure:

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Similarity to this molecule at least:

Name:

GSK-3 Peptide Substrate

Synonyms:

GS-1 Peptide | Phospho-GS2 Substrate Peptide

Type:

Peptide

Mol. Mass.:

3045.17

Organism:

n/a

Description:

n/a

Residue:

27

Sequence:

YRRAAVPPSPSLSRHSSPHQSPEDEEE