Reaction Details
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Target
Glycogen synthase kinase-3 beta [7-25]
Ligand
BDBM7835
Substrate
GSK-3 Peptide Substrate
Meas. Tech.
Kinase Inhibition Assay
Temperature
310.15±n/a K
IC50
100000±n/a nM
Comments
extracted
Citation
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More Info.:
Target
Name:
Glycogen synthase kinase-3 beta [7-25]
Synonyms:
G1T8E2_RABIT | GSK-3, beta | GSK3B | Glycogen Synthase Kinase-3, beta
Type:
Enzyme fragment
Mol. Mass.:
1972.14
Organism:
Oryctolagus cuniculus (rabbit)
Description:
Glycogen Synthase Kinase-3 is the beta isoform of the rabbit enzyme produced in E.coli..
Only partial sequence is available.
Residue:
19
Sequence:
TTSFAESCKPVQQPSAFGS
Inhibitor
Name:
BDBM7835
Synonyms:
1,2-Bis-(phenylcarbonylmethyl)-4-phenyl-1,2,4-triazolidine-3,5-dione | 1,2-bis(2-oxo-2-phenylethyl)-4-phenyl-1,2,4-triazolidine-3,5-dione | Triazolidinedione Derivative 34
Type:
Small organic molecule
Emp. Form.:
C24H19N3O4
Mol. Mass.:
413.4254
SMILES:
O=C(Cn1n(CC(=O)c2ccccc2)c(=O)n(-c2ccccc2)c1=O)c1ccccc1
Substrate
Name:
GSK-3 Peptide Substrate
Synonyms:
GS-1 Peptide | Phospho-GS2 Substrate Peptide
Type:
Peptide
Mol. Mass.:
3045.17
Organism:
n/a
Description:
n/a
Residue:
27
Sequence:
YRRAAVPPSPSLSRHSSPHQSPEDEEE