Reaction Details  Report a problem with these data
Target
Bromodomain testis-specific protein [287-359]
Ligand
BDBM50370181
Substrate
n/a
Meas. Tech.
Plate-Based Time-Resolved Fluorescence Energy Transfer (TR-FRET) Assays
IC50
3082±n/a nM
Citation
 Zhou, J; Brasier, AR; Tian, B; Liu, Z; Chen, H; Rytting, E Inhibitors of bromodomain-containing protein 4 (BRD4) US Patent  US11117865 Publication Date 9/14/2021
Target
Name:
Bromodomain testis-specific protein [287-359]
Synonyms:
BRDT | BRDT_HUMAN | Bromodomain testis-specific protein (BRDT)(BD2)
Type:
n/a
Mol. Mass.:
8713.30
Organism:
Homo sapiens (Human)
Description:
Q58F21[287-359]
Residue:
73
Sequence:
KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVV
  
Inhibitor
Name:
BDBM50370181
Synonyms:
CHEMBL4159382 | US11117865, Compound ZL0454
Type:
Small organic molecule
Emp. Form.:
C18H22N4O3S
Mol. Mass.:
374.457
SMILES:
Cc1cc(\N=N\c2ccc(cc2)S(=O)(=O)NC2CCCC2)c(N)cc1O
Structure:
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