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Target
D(1A) dopamine receptor
Ligand
BDBM601697
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
>10000±n/a nM
Citation
 Kristensen, JL; Jensen, AA; Märcher-Rørsted, E; Leth-Petersen, S 5-HT2A agonists for use in treatment of depression US Patent  US11642336 Publication Date 5/9/2023
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM601697
Synonyms:
US11642336, Compound 8
Type:
Small organic molecule
Emp. Form.:
C14H18F3NO2
Mol. Mass.:
289.2934
SMILES:
COc1cc(c(OC)cc1C1CCCNC1)C(F)(F)F
Structure:
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