Reaction Details  Report a problem with these data
Target
Bromodomain-containing protein 9 [133-239]
Ligand
BDBM50504160
Substrate
n/a
Meas. Tech.
BRD9 Bromodomain TR-FRET Competition Binding Assay
IC50
550±n/a nM
Citation
 Zhou, Q; Bocker, M; Millan, DS; Chan, HM; Soares, L; Netherton, MR; Ruppel, SK; Yang, Z; Lowe, JT; Brucelle, F Methods and compounds for treating disorders US Patent  US11773085 Publication Date 10/3/2023
Target
Name:
Bromodomain-containing protein 9 [133-239]
Synonyms:
BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 (BRD9)(133-239)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12383.34
Organism:
Homo sapiens (Human)
Description:
aa 133-239
Residue:
107
Sequence:
PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
  
Inhibitor
Name:
BDBM50504160
Synonyms:
CHEMBL3133807 | US11773085, Compound B25
Type:
Small organic molecule
Emp. Form.:
C17H20N6O4S
Mol. Mass.:
404.444
SMILES:
CCOC(=O)Nc1cc(nn2c(C)nnc12)-c1ccc(C)c(NS(C)(=O)=O)c1
Structure:
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