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Target
RNA demethylase ALKBH5
Ligand
BDBM50599011
Substrate
n/a
Meas. Tech.
In Vitro Inhibition Assay Method
IC50
>40000±n/a nM
Citation
 Rana, TM BROAD SPECTRUM ANTI-CANCER COMPOUNDS US Patent  US20230322715 Publication Date 10/12/2023
Target
Name:
RNA demethylase ALKBH5
Synonyms:
1.14.11.53 | ABH5 | ALKB5_HUMAN | ALKBH5 | Alkylated DNA repair protein alkB homolog 5 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 | OFOXD1 | RNA demethylase ALKBH5
Type:
PROTEIN
Mol. Mass.:
44270.53
Organism:
Homo sapiens
Description:
ChEMBL_109901
Residue:
394
Sequence:
MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPVSGAKRKYQEDSDPERSDYEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVLPPSYASDRLSGNNRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCSEAAGSPARKVKMRRH
  
Inhibitor
Name:
BDBM50599011
Synonyms:
CHEMBL5204291 | US20230322715, Compound TR-FTO-09
Type:
Small organic molecule
Emp. Form.:
C18H25N3O
Mol. Mass.:
299.4106
SMILES:
Cc1ccc2[nH]cc(CNCC3(COC3)N3CCCC3)c2c1
Structure:
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